Fas Ligand Protein

A transmembrane protein belonging to the tumor necrosis factor superfamily that was originally discovered on cells of the lymphoid-myeloid lineage, including activated T-LYMPHOCYTES and NATURAL KILLER CELLS. It plays an important role in immune homeostasis and cell-mediated toxicity by binding to the FAS RECEPTOR and triggering APOPTOSIS.

Also Known As:

Fas Ligand; CD178 Antigen; CD95 Antigen Ligand; CD95 Ligand; CD95L; Fas Ligand (FasL); FasL Protein; TNF Superfamily, Member 6; Antigen, CD178; Antigens, CD178; CD178 Antigens; Tumor Necrosis Factor Ligand Superfamily Member 6

Carbohydrates: 22516
- Glycoconjugates: 1370
  - Glycoproteins: 25180
    - Membrane Glycoproteins: 2277
      - Fas Ligand Protein: 2704
Amino Acids, Peptides, and Proteins: 1
- Proteins: 496323
  - Intercellular Signaling Peptides and Proteins: 30151
    - Cytokines: 168239
      - Tumor Necrosis Factors: 155
        Fas Ligand Protein: 2704
  - Glycoproteins: 25180
    - Membrane Glycoproteins: 2277
      - Fas Ligand Protein: 2704
  - Membrane Proteins: 10262
    - Membrane Glycoproteins: 2277
      - Fas Ligand Protein: 2704
- Peptides: 84029
  - Intercellular Signaling Peptides and Proteins: 30151
    - Cytokines: 168239
      - Tumor Necrosis Factors: 155
        Fas Ligand Protein: 2704
Biological Factors: 2560
- Intercellular Signaling Peptides and Proteins: 30151
  - Cytokines: 168239
    - Tumor Necrosis Factors: 155
      - Fas Ligand Protein: 2704

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Disease

Drug/Important Bio-Agent (IBA)